| Win | 18-3 | Renan Ferreira  | KO (Punch) |  | PFL Super Fights: Battle of the Giants | Oct 19, 2024 | 1 | 3:32 |  |
| Win | 17-3 | Ciryl Gane  | Decision (Unanimous) |  | UFC 270: N'Gannou vs Gane | Jan 22, 2022 | 5 | 5:00 | Las Vegas, Nevada, United States  |
| Win | 16-3 | Stipe Miocic | KO (Punch) |  | UFC 260: Miocic vs Ngannou 2 | Mar 27, 2021 | 2 | 0:52 | Las Vegas, Nevada, United States |
| Win | 15-3 | Jairzinho Rozenstruik  | KO (Punches) |  | UFC 249: Ferguson vs Gaethje | May 09, 2020 | 1 | 0:20 | Jacksonville, Florida, United States |
| Cancelled Bout | | Jairzinho Rozenstruik | - |  | UFC 249: Ferguson vs Gaethje | Apr 18, 2020 | - | - | Lemoore, California, United States |
| Cancelled Bout | | Jairzinho Rozenstruik | - |  | UFC on ESPN 8: N'Gannou vs Rozenstruik | Mar 28, 2020 | - | - | Columbus, Ohio, United States |
| Win | 14-3 | Junior dos Santos | TKO (Punches) |  | UFC on ESPN 3: Dos Santos vs N'Gannou | Jun 29, 2019 | 1 | 1:11 | Minneapolis, Minnesota, United States |
| Win | 13-3 | Cain Velasquez | KO (Punches) |  | UFC on ESPN 1 | Feb 17, 2019 | 1 | 0:26 | Phoenix, Arizona, United States |
| Win | 12-3 | Curtis Blaydes | TKO (Punches) |  | UFC Fight Night 141: Blaydes vs N'Gannou 2 | Nov 24, 2018 | 1 | 0:45 | Beijing, China  |
| Loss | 11-3 | Derrick Lewis | Decision (Unanimous) |  | UFC 226: Miocic vs Cormier | Jul 07, 2018 | 3 | 5:00 | Last Vegas, Nevada, United States |
| Loss | 11-2 | Stipe Miocic | Decision (Unanimous) |  | UFC 220: Miocic vs N'Gannou | Jan 20, 2018 | 3 | 5:00 | Perth, Western Australia, Australia  |
| Win | 11-1 | Alistair Overeem  | KO (Punch) |  | UFC 218 | Dec 02, 2017 | 1 | 1:42 | Detroit, Michigan, United States |
| Win | 10-1 | Andrey Arlovski  | KO (punches) |  | UFC on FOX 23: Shevchenko vs Peña | Jan 28, 2017 | 1 | 1:32 | Denver, Colorado, United States |
| Win | 9-1 | Anthony Hamilton | Submission (Kimura) |  | UFC Fight Night 102: Lewis vs Abdurakhimov | Dec 09, 2016 | 1 | 1:57 | Albany, New York, United States |
| Win | 8-1 | Bojan Mihajlović  | TKO (punches) |  | UFC on Fox: Holm vs. Shevchenko | Jul 23, 2016 | 1 | 1:34 | Chicago,Illinois, United States |
| Win | 7-1 | Curtis Blaydes | TKO (doctor stoppage) |  | UFC Fight Night: Rothwell vs. dos Santos | Apr 10, 2016 | 2 | 5:00 | Zagreb, Croatia  |
| Win | 6-1 | Luis Henrique | KO (punch) |  | UFC on Fox: dos Anjos vs. Cerrone 2 | Dec 19, 2015 | 2 | 2:53 | Florida, United States |
| Win | 5-1 | William Baldutti | TKO (punches) | | KHK MMA National Tryouts: Finale 2015 | May 28, 2015 | 2 | 1:22 | Madinat Isa, Bahrain  |
| Win | 4-1 | Luc Ngeleka | Submission (standing guillotine choke) | | SHC 10: Carvalho vs. Belo | Sep 20, 2014 | 1 | 0:44 | Geneva, Switzerland  |
| Win | 3-1 | Nicolas Specq | Submission (arm-triangle choke) | | 100% Fight 20: Comeback | Apr 05, 2014 | 2 | 2:10 | Levallois, France |
| Win | 2-1 | Bilal Tahtahi | KO (punch) | | 100% Fight 20: Comeback | Apr 05, 2014 | 1 | 3:58 | Levallois, France |
| Loss | 1-1 | Zoumana Cisse | Decision (unanimous) | | 100% Fight: Contenders 21 | Dec 14, 2013 | 2 | 5:00 | Paris, France |
| Win | 1-0 | Rachid Benzina | Submission (armbar) | | 100% Fight: Contenders 20 | Nov 30, 2013 | 1 | 1:44 | Paris, France |
