| Loss | 18-5 (1) | Tom Aspinall  | KO (Punches) |  | UFC 304: Edwards vs Muhammad 2 | Jul 27, 2024 | 1 | 1:00 | Manchester, England |
| Win | 18-4 (1) | Jailton Almeida  | KO (Punches) |  | UFC 299: O'Malley vs Vera 2 | Mar 09, 2024 | 2 | 0:36 | Miami, Florida, United States  |
| Loss | 17-4 (1) | Sergey Pavlovich  | TKO (Punches) |  | UFC Fight Night: Pavlovich vs. Blaydes | Apr 22, 2023 | 1 | 3:08 | Las Vegas, Nevada, United States |
| Win | 17-3 (1) | Tom Aspinall | TKO (Knee Injury) |  | UFC Fight Night: Blaydes vs Aspinall | Jul 23, 2022 | 1 | 0:15 | London, England, United Kingdom |
| Win | 16-3 (1) | Chris Daukaus | TKO (Punches) |  | UFC Fight Night: Blaydes vs Daukaus | Mar 26, 2022 | 2 | 0:17 | Columbus, Ohio, United States |
| Win | 15-3 (1) | Jairzinho Rozenstruik  | Decision (Unanimous) |  | UFC 266: Volkanovski vs Ortega | Sep 25, 2021 | 3 | 5:00 | Las Vegas, Nevada, United States |
| Loss | 14-3 (1) | Derrick Lewis | KO (Punch) |  | UFC Fight Night 185: Blaydes vs Lewis | Feb 20, 2021 | 2 | 1:26 | Las Vegas, Nevada, United States |
| Cancelled Bout | | Derrick Lewis | - |  | UFC Fight Night 184: Blaydes vs Lewis | Nov 28, 2020 | - | - | Las Vegas, Nevada, United States |
| Win | 14-2 (1) | Alexander Volkov | Decision (Unanimous) |  | UFC Fight Night 173: Blaydes vs Volkov | Jun 20, 2020 | 5 | 5:00 | Las Vegas, Nevada, United States |
| Cancelled Bout | | Alexander Volkov | - | | UFC on ESPN+: Blaydes vs Volkov | Jun 20, 2020 | - | - | Saskatoon, Saskatchewan, Canada |
| Win | 13-2 (1) | Junior dos Santos | TKO (Punches) |  | UFC on ESPN+ 24: Blaydes vs Dos Santos | Jan 25, 2020 | 2 | 1:06 | Raleigh, North Carolina, United States |
| Win | 12-2 (1) | Shamil Abdurahimov | TKO (Elbow and Punch) |  | UFC 242: Khabib vs Poirier | Sep 07, 2019 | 2 | 2:22 | Abu Dhabi, Dubai, United Arab Emirates |
| Win | 11-2 (1) | Justin Willis | Decision (unanimous) |  | UFC Fight Night 148: Thompson vs Pettis | Mar 23, 2019 | 3 | 5:00 | Nashville, Tennessee, United States |
| Loss | 10-2 (1) | Francis Ngannou  | TKO (Punches) |  | UFC Fight Night 141: Blaydes vs N'Gannou 2 | Nov 24, 2018 | 1 | 0:45 | Beijing, China  |
| Win | 10-1 (1) | Alistair Overeem  | TKO (Elbows) |  | UFC 225 | Jun 09, 2018 | 3 | 2:56 | Chicago, Illinois, United States |
| Win | 9-1 (1) | Mark Hunt  | Decision (Unanimous) |  | UFC 221: Rockhold vs Romero | Feb 10, 2018 | 3 | 5:00 | Perth, Western Australia  |
| Win | 8-1 (1) | Alexey Oleinik | TKO (doctor stoppage) |  | UFC 217: Bisping vs St. Pierre | Nov 04, 2017 | 2 | 1:56 | New York City, New York, United States |
| Win | 7-1 (1) | Daniel Omielanczuk  | Decision (Unanimous) |  | UFC 213: Nunes vs Shevchenko 2 | Jul 08, 2017 | 3 | 5:00 | Las Vegas, Nevada, United States |
| NC | 6-1 (1) | Adam Milstead | TKO (knee injury) | | UFC Fight Night 104: Bermudez vs Korean Zombie | Feb 04, 2017 | 2 | 0:59 | Houston, Texas, United States |
| Win | 6-1 | Cody East | TKO (elbows) |  | UFC Fight Night: Lineker vs. Dodson | Oct 01, 2016 | 2 | 2:02 | Oregon, United States |
| Loss | 5-1 | Francis Ngannou | TKO (doctor stoppage) |  | UFC Fight Night: Rothwell vs. dos Santos | Apr 10, 2016 | 2 | 5:00 | Zagreb, Croatia  |
| Win | 5-0 | Luis Cortez | TKO (punches) | | RFA 35: Moises vs. Castillo | Feb 19, 2016 | 3 | 0:41 | Utah, United States |
| Win | 4-0 | Allen Crowder | TKO (punches) | | RDMMA: Battle in the South 10 | Apr 10, 2015 | 2 | - | Carolina, United States |
| Win | 3-0 | Brad Faylor | TKO (punches) | | SCS 23: Redemption | Nov 15, 2014 | 2 | 0:45 | Oklahoma, United Sates |
| Win | 2-0 | William Baptiste | TKO (punches) | | XFO 53 | Oct 11, 2014 | 1 | 2:14 | Illinois, United States |
| Win | 1-0 | Lorenzo Hood | TKO (doctor stoppage) | | XFO 51 | May 31, 2014 | 1 | 1:42 | Illinois, United States |
