| Sieg | 21-13 | Tony Ferguson  | Submission (guillotine choke) |  | UFC 279: Diaz vs Ferguson | Sep 10, 2022 | 4 | 2:52 | Las Vegas, Nevada, United States |
| Niederlage | 20-13 | Leon Edwards  | Decision (Unanimous) |  | UFC 263: Adesanya vs Vettori 2 | Jun 12, 2021 | 5 | 5:00 | Las Vegas, Nevada, United States |
| Cancelled Bout | | Leon Edwards | - |  | UFC 262: Oliveira vs Chandler | May 15, 2021 | - | - | Las Vegas, Nevada, United States |
| Niederlage | 20-12 | Jorge Masvidal | TKO (Doctor Stoppage) |  | UFC 244: Masvidal vs Diaz | Nov 02, 2019 | 3 | 5:00 | New York City, New York, United States |
| Sieg | 20-11 | Anthony Pettis | Decision (Unanimous) |  | UFC 241: Cormier vs Miocic 2 | Aug 17, 2019 | 3 | 5:00 | Anaheim, California, United States |
| Niederlage | 19-11 | Conor McGregor  | Decision (majority) |  | UFC 202: Diaz vs McGregor 2 | Aug 20, 2016 | 5 | 5:00 | Las Vegas, Nevada, United States |
| Sieg | 19-10 | Conor McGregor | Submission (rear-naked choke) |  | UFC 196: McGregor vs Diaz | Mar 05, 2016 | 2 | 4:12 | Las Vegas, United States |
| Sieg | 18-10 | Michael Johnson | Decision (Unanimous) |  | UFC on Fox: Dos Anjos vs Cerrone 2 | Dec 19, 2015 | 3 | 5:00 | Orlando, United States |
| Niederlage | 17-10 | Rafael dos Anjos  | Decision (unanimous) |  | UFC on Fox: Dos Santos vs Miocic | Dec 13, 2014 | 3 | 5:00 | Phoenix, United States |
| Sieg | 17-9 | Gray Maynard | TKO (punches) |  | UFC - The Ultimate Fighter 18 Finale | Nov 30, 2013 | 1 | 2:38 | Las Vegas, United States |
| Niederlage | 16-9 | Josh Thomson | TKO (head kick and punches) | | UFC on Fox 7: Henderson vs Melendez | Apr 20, 2013 | 2 | 3:44 | San Jose, United States |
| Niederlage | 16-8 | Benson Henderson | Decision (unanimous) |  | UFC on Fox 5: Henderson vs Diaz | Dec 08, 2012 | 5 | 5:00 | Washington, United States |
| Sieg | 16-7 | Jim Miller | Submission (guillotine choke) | | UFC on Fox: Diaz vs. Miller | May 05, 2012 | 2 | 4:09 | East Rutherford, United States |
| Sieg | 15-7 | Donald Cerrone | Decision (unanimous) | | UFC 141 | Dec 30, 2011 | 3 | 5:00 | Las Vegas, United States |
| Sieg | 14-7 | Takanori Gomi  | Submission (armbar) |  | UFC 135 | Sep 24, 2011 | 1 | 4:27 | Colorado, United States |
| Niederlage | 13-7 | Rory MacDonald  | Decision (unanimous) |  | UFC 129 | Apr 30, 2011 | 3 | 5:00 | Toronto, Ontario, Canada |
| Niederlage | 13-6 | Dong Hyun Kim  | Decision (unanimous) |  | UFC 125 | Jan 01, 2011 | 3 | 5:00 | Las Vegas, Nevada, United States |
| Sieg | 13-5 | Marcus Davis | Technical submission | | UFC 118 | Aug 28, 2010 | 3 | 4:02 | Massachusetts, United States |
| Sieg | 12-5 | Rory Markham | TKO (punches) | | UFC 111 | Mar 27, 2010 | 1 | 2:47 | New Jersey, United States |
| Niederlage | 11-5 | Gray Maynard | Decision (split) |  | UFC Fight Night: Maynard vs Diaz | Jan 11, 2010 | 3 | 5:00 | Virginia, United States |
| Sieg | 11-4 | Melvin Guillard | Submission (guillotine choke) | | UFC FN: Diaz vs. Guillard | Sep 16, 2009 | 2 | 2:13 | Oklahoma City, United States |
| Niederlage | 10-4 | Joe Stevenson | Decision (unanimous) | | The Ultimate Fighter 9 Finale | Jun 20, 2009 | 3 | 5:00 | Las Vegas, United States |
| Niederlage | 10-3 | Clay Guida | Decision (split) |  | UFC 94 | Jan 31, 2009 | 3 | 5:00 | Las Vegas, United States |
| Sieg | 10-2 | Josh Neer | Decision (split) | | UFC Fight Night: Diaz vs Neer | Sep 17, 2008 | 3 | 5:00 | Nebraska, United States |
| Sieg | 9-2 | Kurt Pellegrino | Submission (triangle choke) | | UFC FN: Florian vs Lauzon | Apr 02, 2008 | 2 | 3:06 | Broomfield, United States |
| Sieg | 8-2 | Alvin Robinson | Submission (triangle choke) | | UFC FN: Swick vs Burkman | Jan 23, 2008 | 1 | 3:39 | Las Vegas, United States |
| Sieg | 7-2 | Junior Assunção | Submission (guillotine choke) | | UFC Fight Night: Thomas vs Florian | Sep 19, 2007 | 1 | 4:10 | Las Vegas, United States |
| Sieg | 6-2 | Manny Gamburyan  | Submission (injury) |  | The Ultimate Fighter | Jun 23, 2007 | 2 | 0:20 | Las Vegas,United States |
| Niederlage | 5-2 | Hermes França | Submission (armbar) | | WEC 24 | Oct 12, 2006 | 2 | 2:46 | Lemoore, United States |
| Sieg | 5-1 | Dennis Davis | Submission (keylock) | | Warrior Cup | Aug 12, 2006 | 1 | 2:00 | Stockton, United States |
| Sieg | 4-1 | Joe Hurley | Submission (triangle choke) | | WEC 21 | Jun 15, 2006 | 2 | 2:03 | Highland, United States |
| Sieg | 3-1 | Gil Rael | TKO (punches) | | WEC 20 | May 05, 2006 | 1 | 3:35 | Lemoore, United States |
| Sieg | 2-1 | Tony Juares | TKO (punches) | | Strikeforce Shamrock vs.Gracie | Mar 10, 2006 | 1 | 3:23 | San Jose, United States |
| Niederlage | 1-1 | Koji Oishi | Decision (unanimous) | | Pancrase Neo Blood Finals | Aug 27, 2005 | 3 | 5:00 | Tokyo, Japan |
| Sieg | 1-0 | Alex Gracia | Submission (triangle choke) | | WEC 12 | Oct 21, 2004 | 3 | 3 | Lemoore, United States |
