| Niederlage | 35-17 | Gilbert Burns  | Decision (Unanimous) |  | UFC 287: Pereira vs Adesanya 2 | Apr 08, 2023 | 3 | 5:00 | Brooklyn, New York , United States  |
| Niederlage | 35-16 | Colby Covington | Decision (Unanimous) |  | UFC 272: Covington vs Masvidal | Mar 05, 2022 | 5 | 5:00 | Las Vegas, Nevada, United States |
| Cancelled Bout | | Leon Edwards  | - |  | UFC 269: Oliveira vs Poirier | Jan 22, 2022 | - | - | Las Vegas, Nevada, United States |
| Niederlage | 35-15 | Kamaru Usman  | KO (Punch) |  | UFC 261: Usman vs Masvidal 2 | Apr 24, 2021 | 2 | 1:02 | Las Vegas, Nevada, United States |
| Niederlage | 35-14 | Kamaru Usman | Decision (Unanimous) |  | UFC 251: Usman vs. Masvidal | Jul 11, 2020 | 5 | 5:00 | Abu Dhabi, Dubai, United Arab Emirates  |
| Sieg | 35-13 | Nate Diaz | TKO (Doctor Stoppage) |  | UFC 244: Masvidal vs Diaz | Nov 02, 2019 | 3 | 5:00 | New York City, New York, United States |
| Sieg | 34-13 | Ben Askren | TKO (Head Kick and Punches) |  | UFC 239: Jones vs Santos | Jul 06, 2019 | 1 | 0:05 | Las Vegas, Nevada, United States |
| Sieg | 33-13 | Darren Till  | KO (Punches) |  | UFC Fight Night 147: Till vs Masvidal | Mar 16, 2019 | 2 | 3:05 | London, England, United Kingdom |
| Niederlage | 32-13 | Stephen Thompson | Decision (unanimous) |  | UFC 217: Bisping vs St. Pierre | Nov 04, 2017 | 3 | 5:00 | New York City, New York, United States |
| Niederlage | 32-12 | Demian Maia | Decision (Split) |  | UFC 211: Miocic vs Dos Santos 2 | May 13, 2017 | 3 | 5:00 | Nashville, Tennessee, United States |
| Sieg | 32-11 | Donald Cerrone | TKO (punches) | | UFC on FOX 23: Shevchenko vs Peña | Jan 28, 2017 | 2 | 1:00 | Denver, Colorado, United States |
| Sieg | 31-11 | Jake Ellenberger | TKO (toe injury) |  | UFC: The Ultimate Fighter 24 Finale | Dec 03, 2016 | 1 | 4:05 | Las Vegas, Nevada, United States |
| Sieg | 30-11 | Ross Pearson | Decision (Unanimous) |  | UFC 201: Lawler vs Woodley | Jul 30, 2016 | 3 | 5:00 | Atlanta, Georgia, United States |
| Niederlage | 29-11 | Lorenz Larkin | Decision (split) |  | UFC Fight Night 88: Almeida vs Garbrandt | May 29, 2016 | 3 | 5:00 | Las Vegas, Nevada, United States |
| Niederlage | 29-10 | Benson Henderson | Decision (Split) |  | UFC Fight Night: Henderson vs Masvidal | Nov 28, 2015 | 5 | 5:00 | Seoul, South Korea |
| Sieg | 29-9 | Cezar Ferreira | KO (elbow and punches) | | The Ultimate Fighter: American Top Team vs. Blackzilians Finale | Jul 12, 2015 | 1 | 4:22 | Nevada, United States |
| Niederlage | 28-9 | Al Iaquinta | Decision (split) |  | UFC Fight Night: Mendes vs. Lamas | Apr 04, 2015 | 3 | 5:00 | Virginia, United States |
| Sieg | 28-8 | James Krause | Decision (unanimous) | | UFC 178 | Sep 27, 2014 | 3 | 5:00 | Nevada, United States |
| Sieg | 27-8 | Daron Cruickshank | Decision (unanimous) | | UFC on Fox: Lawler vs. Brown | Jul 26, 2014 | 3 | 5:00 | California, United States |
| Sieg | 26-8 | Pat Healy | Decision (unanimous) | | UFC on Fox: Werdum vs. Browne | Apr 19, 2014 | 3 | 5:00 | Florida, United States |
| Niederlage | 25-8 | Rustam Khabilov  | Decision (unanimous) |  | UFC: Fight for the Troops 3 | Nov 06, 2013 | 3 | 5:00 | Kentucky, United States |
| Sieg | 25-7 | Michael Chiesa | Submission (D'Arce choke) |  | UFC on Fox: Johnson vs. Moraga | Jul 27, 2013 | 2 | 4:59 | Washington, United States |
| Sieg | 24-7 | Tim Means | Decision (unanimous) | | UFC on Fox: Henderson vs. Melendez | Apr 20, 2013 | 3 | 5:00 | California, United States |
| Sieg | 23-7 | Justin Wilcox | Decision (split) | | Strikeforce: Rockhold vs. Kennedy | Jul 14, 2012 | 3 | 5:00 | Oregon, United States |
| Niederlage | 22-7 | Gilbert Melendez | Decision (unanimous) | | Strikeforce | Dec 17, 2011 | 5 | 5:00 | California, United States |
| Sieg | 22-6 | KJ Noons | Decision (unanimous) | | Strikeforce: Overeem vs. Werdum | Jun 18, 2011 | 3 | 5:00 | Texas, United States |
| Sieg | 21-6 | Billy Evangelista | Decision (unanimous) | | Strikeforce: Feijao vs. Henderson | Mar 05, 2011 | 3 | 5:00 | Ohio, United States |
| Niederlage | 20-6 | Paul Daley | Decision (unanimous) |  | Shark Fights 13: Jardine vs Prangley | Sep 11, 2010 | 3 | 5:00 | Amarillo, Texas, United States |
| Sieg | 20-5 | Naoyuki Kotani  | Decision (split) | | ASTRA | Apr 25, 2010 | 3 | 5:00 | Tokyo, Japan |
| Niederlage | 19-5 | Luis Palomino  | Decision (split) | | G-Force Fights 3 | Apr 02, 2010 | 3 | 5:00 | Florida, United States |
| Sieg | 19-4 | Satoru Kitaoka | KO (punches) | | World Victory Road Presents: Sengoku 11 | Nov 07, 2009 | 2 | 3:03 | Tokyo, Japan |
| Sieg | 18-4 | Eric Reynolds | Submission (rear-naked choke) | | Bellator 12 | Jun 19, 2009 | 3 | 3:33 | Florida, United States |
| Niederlage | 17-4 | Toby Imada | Technical Submission (inverted triangle choke) | | Bellator 5 | May 01, 2009 | 3 | 3:22 | Ohio, United States |
| Sieg | 17-3 | Nick Agallar | TKO (punches) | | Bellator 1 | Apr 03, 2009 | 1 | 1:19 | Florida, United States |
| Sieg | 16-3 | Tae Hyun Bang  | Decision (unanimous) | | World Victory Road Presents: Sengoku 6 | Nov 01, 2008 | 3 | 5:00 | Saitama, Japan |
| Sieg | 15-3 | Ryan Schultz | TKO (punches) | | World Victory Road Presents: Sengoku 5 | Sep 28, 2008 | 1 | 1:57 | Tokyo, Japan |
| Niederlage | 14-3 | Rodrigo Damm | TKO (punch) | | World Victory Road Presents: Sengoku 3 | Jun 08, 2008 | 2 | 4:38 | Saitama, Japan |
| Sieg | 14-2 | Ryan Healy | Decision (unanimous) | | Strikeforce: At The Dome | Feb 23, 2008 | 3 | 5:00 | Washington, United States |
| Sieg | 13-2 | Brant Rose | TKO (punches) | | Crazy Horse Fights | Dec 11, 2007 | 1 | 0:56 | Florida, United States |
| Sieg | 12-2 | Matt Lee | TKO (elbows and punches) | | Strikeforce: Playboy Mansion | Sep 29, 2007 | 1 | 1:33 | California, United States |
| Sieg | 11-2 | Yves Edwards | KO (head kick) | | BodogFIGHT: Alvarez vs. Lee | Jul 14, 2007 | 2 | 2:59 | New Jersey, United States |
| Sieg | 10-2 | Steve Berger | Decision (Unanimous) | | BodogFIGHT: St. Petersburg | Dec 15, 2006 | 3 | 5:00 | St. Petersburg, Russia |
| Sieg | 9-2 | Keith Wisniewski | Decision (majority) | | BodogFIGHT: To the Brink of War | Aug 22, 2006 | 3 | 5:00 | San Jose, Costa Rica |
| Sieg | 8-2 | Nuri Shakir | Decision (unanimous) | | AFC 17 | Jun 24, 2006 | 3 | 5:00 | Florida, United States |
| Sieg | 7-2 | David Gardner | TKO (punches) | | AFC 15 | Feb 18, 2006 | 2 | 0:14 | Florida, United States |
| Niederlage | 6-2 | Paul Rodriguez | Submission (rear-naked choke) | | AFC 13 | Jul 30, 2005 | 1 | 2:27 | Florida, United States |
| Sieg | 6-1 | Joe Lauzon | TKO (punches) | | AFC 12 | Apr 30, 2005 | 2 | 3:57 | Florida, United States |
| Niederlage | 5-1 | Raphael Assunção | Decision (unanimous) | | Full Throttle 1 | Apr 21, 2005 | 3 | 5:00 | Duluth, Georgia, United States |
| Sieg | 5-0 | Justin Wisniewski | Decision (majority) | | AFC 8 | May 01, 2004 | 2 | 5:00 | Florida, United States |
| Sieg | 4-0 | Julian Ortega | Decision (unanimous) | | AFC 6 | Dec 03, 2003 | 2 | 5:00 | Florida, United States |
| Sieg | 3-0 | Rolando Delgado | TKO (punches) | | AFC 5 | Sep 05, 2003 | 2 | 2:14 | Florida, United States |
| Sieg | 2-0 | Brian Geraghty | Decision (unanimous) | | AFC 4 | Jul 19, 2003 | 2 | 5:00 | Florida, United States |
| Sieg | 1-0 | Brandon Bledsoe | KO (punches) | | AFC 3 | May 24, 2003 | 1 | 3:55 | Florida, United States |
