| Niederlage | 22-6 | Dustin Poirier  | TKO (Doctor Stoppage) |  | UFC 264: Poirier vs McGregor 3 | Jul 10, 2021 | 1 | 5:00 | Las Vegas, Nevada, United States |
| Niederlage | 22-5 | Dustin Poirier | KO (Punches) |  | UFC 257: McGregor vs Poirier 2 | Jan 23, 2021 | 2 | 2:32 | Abu Dhabi, Dubai, United Arab Emirates  |
| Sieg | 22-4 | Donald Cerrone | TKO (Punches) |  | UFC 246: McGregor vs Cerrone | Jan 18, 2020 | 1 | 0:40 | Las Vegas, Nevada, United States |
| Niederlage | 21-4 | Khabib Nurmagomedov  | Submission (Neck Crank) |  | UFC 229: Khabib vs McGregor | Oct 06, 2018 | 4 | 3:03 | Las Vegas, Nevada, United States |
| Sieg | 21-3 | Eddie Alvarez | KO (punches) |  | UFC 205: Alvarez vs McGregor | Nov 12, 2016 | 2 | 3:04 | New York, New York, United States |
| Sieg | 20-3 | Nate Diaz | Decision (majority) |  | UFC 202: Diaz vs McGregor 2 | Aug 20, 2016 | 5 | 5:00 | Las Vegas, Nevada, United States |
| Niederlage | 19-3 | Nate Diaz | Submission (rear-naked choke) |  | UFC 196: McGregor vs Diaz | Mar 05, 2016 | 2 | 4:12 | Las Vegas, United States |
| Sieg | 19-2 | Jose Aldo  | KO (punches) |  | UFC 194: Aldo vs McGregor | Dec 12, 2015 | 1 | 0:13 | Arlington, Texas, United States |
| Sieg | 18-2 | Chad Mendes | TKO (Punches) |  | UFC 189: Mendes vs McGregor | Jul 11, 2015 | 2 | 4:57 | Las Vegas, United States |
| Sieg | 17-2 | Dennis Siver  | TKO (punches) |  | UFC Fight Night 59: McGregor vs Siver | Jan 18, 2015 | 2 | 1:54 | Boston, United States |
| Sieg | 16-2 | Dustin Poirier | TKO (punches) |  | UFC 178 | Dec 27, 2014 | 1 | 1:46 | Las Vegas, United States |
| Sieg | 15-2 | Diego Brandão | TKO (punches) |  | UFC Fight Night: McGregor vs. Brandao | Jul 19, 2014 | 1 | 4:05 | Dublin, Ireland  |
| Sieg | 14-2 | Max Holloway | Decision (unanimous) | | UFC Fight Night: Shogun vs. Sonnen | Aug 17, 2013 | 3 | 5:00 | Boston, United States |
| Sieg | 13-2 | Marcus Brimage | TKO (punches) |  | UFC on Fuel TV: Mousasi vs. Latifi | Apr 06, 2013 | 1 | 1:07 | Stockholm, Sweden  |
| Sieg | 12-2 | Ivan Buchinger  | KO (punch) |  | CWFC 51 | Dec 31, 2012 | 1 | 3:40 | Dublin, Ireland |
| Sieg | 11-2 | Dave Hill | Submission (rear-naked choke) |  | CWFC 47 | Jun 02, 2012 | 2 | 4:10 | Dublin, Ireland |
| Sieg | 10-2 | Steve O'Keefe | KO (elbows) | | CWFC 45 | Feb 18, 2012 | 1 | 1:35 | Kentish Town, England  |
| Sieg | 9-2 | Aaron Jahnsen | TKO (punches) | | Cage Warriors: Fight Night 2 | Sep 08, 2011 | 1 | 3:29 | Amman, Jordan  |
| Sieg | 8-2 | Artur Sowinski  | TKO (punches) | | Celtic Gladiator 2: Clash of the Giants | Jun 11, 2011 | 2 | 1:12 | Portlaoise, Ireland |
| Sieg | 7-2 | Patrick Doherty | KO (punch) | | Immortal Fighting Championship 4 | Apr 16, 2011 | 1 | 0:04 | Letterkenny, Ireland |
| Sieg | 6-2 | Mike Wood | KO (punches) | | Cage Contender 8 | Mar 12, 2011 | 1 | 0:16 | Dublin, Ireland |
| Sieg | 5-2 | Hugh Brady | TKO (punches) | | Chaos FC 8 | Feb 12, 2011 | 1 | 2:31 | Derry, Northern Ireland |
| Niederlage | 4-2 | Joseph Duffy | Submission (arm-triangle choke) | | Cage Warriors 39: The Uprising | Nov 27, 2010 | 1 | 0:38 | Cork, Ireland |
| Sieg | 4-1 | Connor Dillon | TKO (corner stoppage) | | Chaos FC 7 | Oct 09, 2010 | 1 | 4:22 | Derry, Northern Ireland |
| Sieg | 3-1 | Stephen Bailey | TKO (punches) | | K.O.: The Fight Before Christmas | Dec 12, 2008 | 1 | 1:22 | Dublin, Ireland |
| Niederlage | 2-1 | Artemij Sitenkov  | Submission (kneebar) | | Cage of Truth 3 | Jun 28, 2008 | 1 | 1:09 | Dublin, Ireland |
| Sieg | 2-0 | Mo Taylor | TKO (punches) | | Cage Rage Contenders - Ireland vs. Belgium | May 03, 2008 | 1 | 1:06 | Dublin, Ireland |
| Sieg | 1-0 | Gary Morris | TKO (punches) | | Cage of Truth 2 | Mar 08, 2008 | 2 | N/A | Dublin, Ireland |
