| Niederlage | 23-10-1 | Dilano Taylor | TKO (Punches) |  | PFL 8: 2022 | Aug 13, 2022 | 1 | 3:59 | Cardiff, Wales  |
| Niederlage | 23-9-1 | Sadibou Sy  | Decision (Unanimous) |  | PFL 6: 2022 Regular Season | Jul 01, 2022 | 3 | 5:00 | Atlanta, Georgia, United States  |
| Sieg | 23-8-1 | Brett Cooper | Submission (Rear-Naked Choke) |  | PFL 3: 2022 Regular Season | May 06, 2022 | 1 | 2:33 | Arlington, Texas, United States |
| Niederlage | 22-8-1 | Ray Cooper III | Decision (Unanimous) |  | PFL 2021 #7: Playoffs | Aug 13, 2021 | 3 | 5:00 | Hollywood, Florida, United States |
| Niederlage | 22-7-1 | Gleison Tibau  | Decision (Split) |  | PFL 2021 #5 | Jun 17, 2021 | 3 | 5:00 | Atlantic City, New Jersey, United States |
| Sieg | 22-6-1 | Curtis Millender | Submission (Rear-Naked Choke) |  | PFL 2021 #2 | Apr 29, 2021 | 1 | 3:38 | Atlantic City, New Jersey, United States |
| Niederlage | 21-6-1 | Douglas Lima | Decision (Unanimous) |  | Bellator Welterweight World Grand Prix Tournament | Oct 26, 2019 | 5 | 5:00 | Uncasville, Connecticut, United States |
| Sieg | 21-5-1 | Neiman Gracie | Decision (Unanimous) |  | Bellator Welterweight World Grand Prix Tournament | Jun 14, 2019 | 5 | 5:00 | New York City, New York, United States |
| Unentschieden | 20-5-1 | Jon Fitch | Draw (Majority) |  | Bellator Welterweight World Grand Prix Tournament | Apr 27, 2019 | 5 | 5:00 | San Jose, California, United States |
| Niederlage | 20-5 | Gegard Mousasi  | TKO (punches and elbows) |  | Bellator 206: Mousasi vs MacDonald | Sep 29, 2018 | 2 | 2:32 | Jose, California, United States |
| Sieg | 20-4 | Douglas Lima | Decision (unanimous) |  | Bellator 192: Lima vs MacDonald | Jan 20, 2018 | 3 | 5:00 | Inglewood, California, United States |
| Sieg | 19-4 | Paul Daley  | Submission (rear-naked choke |  | Bellator 179: Daley vs MacDonald | May 19, 2017 | 2 | 1:45 | London, England  |
| Niederlage | 18-4 | Stephen Thompson | Decision (unanimous) |  | UFC Fight Night 89: MacDonald vs Thompson | Jun 18, 2016 | 5 | 5:00 | Ottawa, Ontario, Canada |
| Niederlage | 18-3 | Robbie Lawler | TKO (Punches) |  | UFC 189: Mendes vs McGregor | Jul 11, 2015 | 5 | 1:00 | Las Vegas, United States |
| Sieg | 18-2 | Tarec Saffiedine  | TKO (punches) |  | UFC Fight Night: MacDonald vs Saffiedine | Oct 04, 2014 | 3 | 1:28 | Halifax, Canada  |
| Sieg | 17-2 | Tyron Woodley | Decision (unanimous) |  | UFC 174 | Jun 14, 2014 | 3 | 5:00 | Vancouver, British Columbia, Canada |
| Sieg | 16-2 | Demian Maia | Decision (unanimous) |  | UFC 170: Rousey vs McMann | Feb 22, 2014 | 3 | 5:00 | Las Vegas, United States |
| Niederlage | 15-2 | Robbie Lawler | Decision (split) |  | UFC 167 | Nov 16, 2013 | 3 | 5:00 | Las Vegas, Nevada, US |
| Sieg | 15-1 | Jake Ellenberger | Decision (unanimous) |  | UFC on Fox: Johnson vs. Moraga | Jul 27, 2013 | 3 | 5:00 | Seattle, Washington, US |
| Sieg | 14-1 | B.J. Penn | Decision (unanimous) |  | UFC on Fox: Henderson vs. Diaz | Dec 08, 2012 | 3 | 5:00 | Seattle, Washington, US |
| Sieg | 13-1 | Che Mills | TKO (punches) |  | UFC 145 | Apr 21, 2012 | 2 | 2:20 | Atlanta, Georgia, United States |
| Sieg | 12-1 | Mike Pyle | TKO (punches) |  | UFC 133 | Aug 06, 2011 | 1 | 3:54 | Philadelphia, Pennsylvania, US |
| Sieg | 11-1 | Nate Diaz | Decision (unanimous) |  | UFC 129 | Apr 30, 2011 | 3 | 5:00 | Toronto, Ontario, Canada |
| Niederlage | 10-1 | Carlos Condit | TKO (punches) |  | UFC 115 | Jun 12, 2010 | 3 | 4:53 | British Columbia, Canada |
| Sieg | 10-0 | Mike Guymon | Submission (armbar) |  | UFC Fight Night: Maynard vs. Diaz | Jan 11, 2010 | 1 | 4:27 | Fairfax, Virginia, United States |
| Sieg | 9-0 | Nick Hinchliffe | KO (punches) | | KOTC Canada: Disturbed | Sep 26, 2009 | 2 | 2:08 | Edmonton, Alberta, Canada |
| Sieg | 8-0 | Elmer Waterhen | Submission (armbar) | | KOTC Canada: Island Pride | May 08, 2009 | 1 | 1:27 | Nanaimo, Canada |
| Sieg | 7-0 | Clay French | KO (punches) | | KOTC Canada: Grinder | Nov 28, 2008 | 2 | 4:26 | Calgary, Alberta, Canada |
| Sieg | 6-0 | Kajan Johnson | TKO (punches) | | KOTC Canada: Avalanche | Dec 15, 2007 | 3 | 1:48 | Moncton, Moncton, Canada |
| Sieg | 5-0 | Yoon Heo | TKO (knees) | | KOTC Canada: Icebreaker | Nov 03, 2006 | 2 | 0:19 | Prince George, Canada |
| Sieg | 4-0 | Quinton Moreno | Submission (triangle choke) | | KOTC Canada: Insurrection | Oct 06, 2006 | 1 | N/A | Vernon, Canada |
| Sieg | 3-0 | Jordan Mein | Submission (rear naked choke) | | Rumble in the Cage 17 | Jun 17, 2006 | 1 | 4:04 | Lethbridge, Alberta, Canada |
| Sieg | 2-0 | Ken Tran | Submission (rear naked choke) | | KOTC Canada: Anarchy | Feb 11, 2006 | 1 | 2:33 | Prince George, Canada |
| Sieg | 1-0 | Terry Thiara | Submission (rear naked choke) | | Extreme Fighting Challenge 4 | Oct 15, 2005 | 1 | 2:11 | Prince George, Canada |
