| Niederlage | 25-14 | Stevie Ray  | Decision (Unanimous) |  | PFL 7: 2022 | Aug 05, 2022 | 3 | 5:00 | New York City, New York, United States  |
| Niederlage | 25-13 | Stevie Ray | Submission (body triangle) |  | PFL 5: 2022 Regular Season | Jun 24, 2022 | 2 | 3:57 | Atlanta, Georgia, United States |
| Sieg | 25-12 | Myles Price  | Submission (Triangle Choke) |  | PFL 3: 2022 Regular Season | May 06, 2022 | 1 | 4:17 | Arlington, Texas, United States |
| Niederlage | 24-12 | Raush Manfio  | Decision (Split) |  | PFL 2021 #6 | Jun 25, 2021 | 3 | 5:00 | Atlantic City, New Jersey, United States |
| Cancelled Bout | | Alex Martinez  | - |  | PFL 2021 #4 | Jun 10, 2021 | - | - | Atlantic City, New Jersey, United States |
| Niederlage | 24-11 | Clay Collard | Decision (Unanimous) |  | PFL 2021 #1 | Apr 23, 2021 | 3 | 5:00 | Atlantic City, New Jersey, United States |
| Sieg | 24-10 | Alex Morono | Decision (Unanimous) |  | UFC Fight Night 183: Thompson vs Neal | Dec 12, 2020 | 3 | 5:00 | Las Vegas, Nevada, United States |
| Sieg | 23-10 | Donald Cerrone | Decision (Unanimous) |  | UFC 249: Ferguson vs Gaethje | May 09, 2020 | 3 | 5:00 | Jacksonville, Florida, United States |
| Niederlage | 22-10 | Diego Ferreira | Submission (Rear-Naked Choke) |  | UFC 246: McGregor vs Cerrone | Jan 18, 2020 | 2 | 1:46 | Las Vegas, Nevada, United States |
| Niederlage | 22-9 | Nate Diaz | Decision (Unanimous) |  | UFC 241: Cormier vs Miocic 2 | Aug 17, 2019 | 3 | 5:00 | Anaheim, California, United States |
| Sieg | 22-8 | Stephen Thompson | KO (punches) |  | UFC Fight Night 148: Thompson vs Pettis | Mar 23, 2019 | 2 | 4:55 | Nashville, Tennessee, United States |
| Niederlage | 21-8 | Tony Ferguson | TKO (Corner Stoppage) |  | UFC 229: Khabib vs McGregor | Oct 06, 2018 | 2 | 5:00 | Las Vegas, Nevada, United States |
| Sieg | 21-7 | Michael Chiesa | Submission (Triangle Armbar) |  | UFC 226: Miocic vs Cormier | Jul 07, 2018 | 2 | 0:52 | Last Vegas, Nevada, United States |
| Niederlage | 20-7 | Dustin Poirier | Submission (Body Triangle) |  | UFC Fight Night 120: Poirier vs Pettis | Nov 11, 2017 | 3 | 2:08 | Norfolk, Virginia, United States |
| Sieg | 20-6 | Jim Miller | Decision (Unanimous) |  | UFC 213: Nunes vs Shevchenko 2 | Jul 08, 2017 | 3 | 5:00 | Las Vegas, Nevada, United States |
| Niederlage | 19-6 | Max Holloway | TKO (Kick to the Body and Punches) |  | UFC 206: Holloway vs Pettis | Dec 10, 2016 | 3 | 4:50 | Toronto, Ontario, Canada |
| Sieg | 19-5 | Charles Oliveira | Submission (guillotine choke) |  | UFC on FOX 21: Maia vs Condit | Aug 27, 2016 | 3 | 1:49 | Vancouver, British Columbia, Canada |
| Niederlage | 18-5 | Edson Barboza | Decision (unanimous) |  | UFC 197: Jones vs Saint Preux | Apr 23, 2016 | 3 | 5:00 | New York City, United States |
| Niederlage | 18-4 | Eddie Alvarez | Decision (spilt) |  | UFC Fight Night 81: Dillashaw vs Cruz | Jan 17, 2016 | 3 | 5:00 | Boston, United States |
| Niederlage | 18-3 | Rafael dos Anjos | Decision (unanimous) |  | UFC 185: Pettis vs dos Anjos | Mar 14, 2015 | 5 | 5:00 | Dallas, Texas, United States |
| Sieg | 18-2 | Gilbert Melendez | Submission (guillotine choke) |  | UFC 181: Hendricks vs Lawler II | Dec 09, 2014 | 2 | 1:53 | Las Vegas, United States |
| Sieg | 17-2 | Benson Henderson | Submission (armbar) | | UFC 164: Henderson vs Pettis 2 | Aug 31, 2013 | 1 | 4:31 | Milwaukee, United States |
| Sieg | 16-2 | Donald Cerrone | TKO (kick to the body & punches) | | UFC on Fox: Johnson vs Dodson | Jan 26, 2013 | 1 | 2:35 | Chicago, United States |
| Sieg | 15-2 | Joe Lauzon | KO (head kick and punches) |  | UFC 144 | Feb 26, 2012 | 1 | 1:21 | Saitama, Japan |
| Sieg | 14-2 | Jeremy Stephens | Decision (split) |  | UFC 136 | Oct 08, 2011 | 3 | 5:00 | Houston, United States |
| Niederlage | 13-2 | Clay Guida | Decision (unanimous) | | The Ultimate Fighter 13 Finale | Jun 04, 2011 | 3 | 5:00 | Las Vegas, United States |
| Sieg | 13-1 | Benson Henderson | Decision (unanimous) |  | WEC 53 | Dec 16, 2010 | 5 | 5:00 | Glendale, United States |
| Sieg | 12-1 | Shane Roller | Submission (triangle choke) |  | WEC 50 | Aug 18, 2010 | 3 | 4:51 | Las Vegas, United States |
| Sieg | 11-1 | Alex Karalexis | Submission (triangle choke) | | WEC 48 | Apr 24, 2010 | 2 | 1:35 | Sacramento, United States |
| Sieg | 10-1 | Danny Castillo | KO (head kick and punches) | | WEC 47 | Mar 06, 2010 | 1 | 2:27 | Columbus, United States |
| Niederlage | 9-1 | Bart Palaszewski | Decision (split) | | WEC 45 | Dec 19, 2009 | 3 | 5:00 | Las Vegas, United States |
| Sieg | 9-0 | Mike Campbell | Submission (triangle choke) | | WEC 41 | Jun 07, 2009 | 1 | 1:49 | Sacramento, United States |
| Sieg | 8-0 | Gabe Walbridge | TKO (punches) | | GFS: Season's Beatings | Dec 13, 2008 | 1 | 0:56 | Milwaukee, United States |
| Sieg | 7-0 | Jay Ellis | Submission (punches) | | GFS 55 | Oct 04, 2008 | 1 | 1:12 | Milwaukee, United States |
| Sieg | 6-0 | Sherron Leggett | Decision (split) | | GFS: Fight Club | Jun 21, 2008 | 3 | 5:00 | Milwaukee, United States |
| Sieg | 5-0 | Mike Lambrecht | KO (head kick) | | GFS: Knockout Kings | Mar 29, 2008 | 1 | 1:49 | Milwaukee, United States |
| Sieg | 4-0 | George Barrazza | TKO (punches) | | GFS: The Warriors | Feb 16, 2008 | 1 | 4:31 | Milwaukee, United States |
| Sieg | 3-0 | Michael Skinner | Submission (punches) | | GFS: Seasons Beatings | Dec 01, 2007 | 1 | 0:36 | Milwaukee, United States |
| Sieg | 2-0 | Lonny Amdahl | Submission (injury) | | GFS: Rumble in the Cage | Aug 17, 2007 | 1 | 0:12 | Green Bay, United States |
| Sieg | 1-0 | Tom Erspamer | TKO (punches) | | GFS: Super Brawl | Jan 27, 2007 | 1 | 0:24 | United States |
