| Loss | 19-7-1 | Vicente Luque  | Submission (Brabo Choke) |  | UFC 260: Miocic vs Ngannou 2 | Mar 27, 2021 | 1 | 3:56 | Las Vegas, Nevada, United States  |
| Loss | 19-6-1 | Colby Covington | TKO (Rib Injury) |  | UFC Fight Night 178: Covington vs Woodley | Sep 19, 2020 | 5 | 1:19 | Las Vegas, Nevada, United States |
| Loss | 19-5-1 | Gilbert Burns | Decision (Unanimous) |  | UFC on ESPN 9: Woodley vs Burns | May 30, 2020 | 5 | 5:00 | Jacksonville, Florida, United States |
| Cancelled Bout | | Leon Edwards  | - |  | UFC on ESPN+ 29: Woodley vs Edwards | Mar 21, 2020 | - | - | London, England  |
| Loss | 19-4-1 | Kamaru Usman  | Decision (Unanimous) |  | UFC 235 | Mar 02, 2019 | 5 | 5:00 | Las Vegas, Nevada, United States |
| Win | 19-3-1 | Darren Till | Submission (Brabo Choke) |  | UFC 228: Woodley vs Till | Sep 08, 2018 | 2 | 4:19 | Dallas, Texas, United States |
| Win | 18-3-1 | Demian Maia | Decision (Unanimous) |  | UFC 214: Cormier vs Jones 2 | Jul 29, 2017 | 5 | 5:00 | Anaheim, California, United States |
| Win | 17-3-1 | Stephen Thompson | Decision (majority) |  | UFC 209: Woodley vs Thompson 2 | Mar 04, 2017 | 5 | 5:00 | Las Vegas, Nevada, United States |
| Draw | 16-3-1 | Stephen Thompson | Draw (Majority) |  | UFC 205: Alvarez vs McGregor | Nov 12, 2016 | 5 | 5:00 | New York, New York, United States |
| Win | 16-3 | Robbie Lawler | KO (Punches) | | UFC 201: Lawler vs Woodley | Jul 30, 2016 | 1 | 2:12 | Atlanta, Georgia, United States |
| Win | 15-3 | Kelvin Gastelum | Decision (split) | | UFC 183: Silva vs Diaz | Jan 31, 2015 | 3 | 5:00 | Las Vegas, United States |
| Win | 14-3 | Dong Hyun Kim  | TKO (punches) |  | UFC Fight Night: Bisping vs Le | Aug 23, 2014 | 1 | 1:01 | Macau, SAR, China  |
| Loss | 13-3 | Rory MacDonald  | Decision (unanimous) |  | UFC 174 | Jun 14, 2014 | 3 | 5:00 | Vancouver, British Columbia, Canada |
| Win | 13-2 | Carlos Condit | TKO (leg injury) |  | UFC 171 | Mar 15, 2014 | 2 | 2:00 | Dallas, Texas, United States |
| Win | 12-2 | Josh Koscheck | KO (punches) |  | UFC 167 | Nov 16, 2013 | 1 | 4:38 | Las Vegas, Nevada, US |
| Loss | 11-2 | Jake Shields | Decision (split) |  | UFC 161 | Jun 15, 2013 | 3 | 5:00 | Winnipeg, Canada |
| Win | 11-1 | Jay Hieron | KO (punches) | | UFC 156 | Feb 02, 2013 | 1 | 0:36 | Las Vegas, Nevada, US |
| Loss | 10-1 | Nate Marquardt | KO (elbows & punches) |  | Strikeforce: | Jul 14, 2012 | 4 | 1:39 | Portland,Oregon, United States |
| Win | 10-0 | Jordan Mein | Decision (split) | | Strikeforce: Rockhold vs. Jardine | Jan 07, 2012 | 3 | 5:00 | Las Vegas, Nevada, US |
| Win | 9-0 | Paul Daley | Decision (unanimous) |  | Strikeforce: Fedor vs. Henderson | Jul 30, 2011 | 3 | 5:00 | Hoffman Estates, Illinois, US |
| Win | 8-0 | Tarec Saffiedine  | Decision (unanimous) |  | Strikeforce Challengers: Woodley vs. Saffiedine | Jan 07, 2011 | 3 | 5:00 | Nashville, United States |
| Win | 7-0 | André Galvão | TKO (punches) | | Strikeforce: Diaz vs. Noons II | Oct 09, 2010 | 1 | 1:48 | San Jose, California, US |
| Win | 6-0 | Nathan Coy | Decision (split) | | Strikeforce Challengers: Lindland vs. Casey | May 21, 2010 | 3 | 5:00 | Portland, Oregon, US |
| Win | 5-0 | Rudy Bears | Submission (arm triangle choke) | | Strikeforce Challengers: Woodley vs. Bears | Nov 20, 2009 | 1 | 2:52 | Kansas City, Kansas, US |
| Win | 4-0 | Zach Light | Submission (armbar) | | Strikeforce Challengers: Kennedy vs. Cummings | Sep 25, 2009 | 2 | 3:38 | Bixby, Oklahoma, US |
| Win | 3-0 | Sal Woods | Submission (d'arce choke) | | Strikeforce: Lawler vs. Shields | Jun 06, 2009 | 1 | 4:20 | St. Louis, Missouri, US |
| Win | 2-0 | Jeff Carstens | Submission (rear naked choke) | | Respect Is Earned: Brotherly Love Brawl | Apr 30, 2009 | 1 | 0:48 | Oaks, Pennsylvania, US |
| Win | 1-0 | Steve Schnider | Submission (punches) | | Headhunter Productions: The Patriot Act 1 | Feb 07, 2009 | 1 | 1:09 | Columbia, Missouri, US |
