| Loss | 17-9-1 | Gabriel Bonfim  | Decision (Split) |  | UFC Fight Night: Lewis vs Teixeira | Jul 12, 2025 | 3 | 5:00 | Nashville, Tennessee, United States  |
| Loss | 17-8-1 | Joaquin Buckley | TKO (Punches) |  | UFC 307: Pereira vs Rountree | Oct 05, 2024 | 3 | 2:17 | Salt Lake City, Utah, United States |
| Loss | 17-7-1 | Shavkat Rakhmonov  | Submission (Rear-Naked Choke) |  | UFC 296: Edwards vs Covington | Dec 16, 2023 | 2 | 4:56 | Las Vegas, Nevada, United States |
| Cancelled Bout | | Michel Pereira | - |  | UFC 291: Poirier vs Gaethje 2 | Jul 29, 2023 | - | - | Salt Lake City, Utah, United States |
| Win | 17-6-1 | Kevin Holland | TKO (Corner Stoppage) |  | UFC Fight Night: Thompson vs Holland | Dec 03, 2022 | 4 | 5:00 | Orlando, Florida, United States |
| Loss | 16-6-1 | Belal Muhammad | Decision (Unanimous) |  | UFC Fight Night: Lewis vs Daukaus | Dec 18, 2021 | 3 | 5:00 | Las Vegas, Nevada, United States |
| Loss | 16-5-1 | Gilbert Burns | Decision (Unanimous) |  | UFC 264: Poirier vs McGregor 3 | Jul 10, 2021 | 3 | 5:00 | Las Vegas, Nevada, United States |
| Win | 16-4-1 | Geoff Neal | Decision (Unanimous) |  | UFC Fight Night 183: Thompson vs Neal | Dec 12, 2020 | 5 | 5:00 | Las Vegas, Nevada, United States |
| Win | 15-4-1 | Vicente Luque | Decision (Unanimous) |  | UFC 244: Masvidal vs Diaz | Nov 02, 2019 | 3 | 5:00 | New York City, New York, United States |
| Loss | 14-4-1 | Anthony Pettis | KO (punches) |  | UFC Fight Night 148: Thompson vs Pettis | Mar 23, 2019 | 2 | 4:55 | Nashville, Tennessee, United States |
| Loss | 14-3-1 | Darren Till  | Decision (Unanimous) |  | UFC Fight Night 130 | May 27, 2018 | 5 | 5:00 | Liverpool, England, United Kingdom |
| Win | 14-2-1 | Jorge Masvidal | Decision (unanimous) |  | UFC 217: Bisping vs St. Pierre | Nov 04, 2017 | 3 | 5:00 | New York City, New York, United States |
| Loss | 13-2-1 | Tyron Woodley | Decision (majority) |  | UFC 209: Woodley vs Thompson 2 | Mar 04, 2017 | 5 | 5:00 | Las Vegas, Nevada, United States |
| Draw | 13-1-1 | Tyron Woodley | Draw (Majority) |  | UFC 205: Alvarez vs McGregor | Nov 12, 2016 | 5 | 5:00 | New York, New York, United States |
| Win | 13-1 | Rory MacDonald  | Decision (unanimous) |  | UFC Fight Night 89: MacDonald vs Thompson | Jun 18, 2016 | 5 | 5:00 | Ottawa, Ontario, Canada |
| Win | 12-1 | Johny Hendricks | TKO (punches) |  | UFC Fight Night 82: Hendricks vs Thompson | Feb 06, 2016 | 1 | 3:31 | Las Vegas, United States |
| Win | 11-1 | Jake Ellenberger | KO (spinning hook kick) |  | The Ultimate Fighter: American Top Team vs. Blackzilians Finale | Jul 12, 2015 | 1 | 4:29 | Las Vegas, Nevada, United States |
| Win | 10-1 | Patrick Côté | Decision (unanimous) |  | UFC 178: Johnson vs Cariaso | Sep 27, 2014 | 3 | 5:00 | Las Vegas, United States |
| Win | 9-1 | Robert Whittaker  | TKO (punches) |  | UFC 170 | Feb 22, 2014 | 1 | 3:43 | Las Vegas, Nevada, United States |
| Win | 8-1 | Chris Clements | KO (punches) | | UFC 165 | Sep 21, 2013 | 2 | 1:27 | Toronto, Ontario, Canada |
| Win | 7-1 | Nah-Shon Burrell | Decision (unanimous) | | UFC 160 | May 25, 2013 | 3 | 5:00 | Las Vegas, Nevada, United States |
| Loss | 6-1 | Matt Brown | Decision (unanimous) | | UFC 145 | Apr 21, 2012 | 3 | 5:00 | Atlanta, Georgia, United States |
| Win | 6-0 | Dan Stittgen | KO (head kick) | | UFC 143 | Feb 04, 2012 | 1 | 4:13 | Las Vegas, Nevada, United States |
| Win | 5-0 | Patrick Mandio | Decision (unanimous) | | Fight Party: Masquerade Fight Party | Oct 01, 2011 | 3 | 5:00 | Atlanta, Georgia, United States |
| Win | 4-0 | William Kuhn | Decision (unanimous) | | Xtreme Chaos 2 | Jul 15, 2011 | 3 | 5:00 | Anderson, South Carolina, United States |
| Win | 3-0 | Marques Worrell | Submission (rear-naked choke) | | Fight Party: Greenville Kage Fighting 2 | Sep 18, 2010 | 2 | 3:08 | Greenville, South Carolina, United States |
| Win | 2-0 | Daniel Finz | TKO (punches) | | Fight Party: Xtreme Cage Fighting 2 | May 22, 2010 | 1 | 3:45 | Greenville, South Carolina, United States |
| Win | 1-0 | Jeremy Joles | TKO (punches) | | Fight Party: Greenville Kage Fighting | Feb 05, 2010 | 2 | 3:40 | Greenville, South Carolina, United States |
