| Loss | 30-12 | Omar Nurmagomedov  | Submission (Rear-Naked Choke) |  | Bellator Lightweight World Grand Prix Tournament | Mar 10, 2023 | 1 | 2:37 | San Jose, California, United States  |
| Win | 30-11 | Peter Queally  | Decision (Unanimous) |  | Bellator 285: Henderson vs Queally | Sep 23, 2022 | 5 | 5:00 | Dublin, Ireland |
| Win | 29-11 | Islam Mamedov | Decision (Split) |  | Bellator 273: Bader vs Moldavsky | Jan 29, 2022 | 3 | 5:00 | Phoenix, Arizona, United States |
| Loss | 28-11 | Brent Primus | Decision (Unanimous) |  | Bellator 268: Nemkov vs Anglickas | Oct 16, 2021 | 3 | 5:00 | Phoenix, Arizona, United States |
| Loss | 28-10 | Jason Jackson  | Decision (Unanimous) |  | Bellator 253: Caldwell vs McKee | Nov 19, 2020 | 3 | 5:00 | Uncasville, Connecticut, United States |
| Loss | 28-9 | Michael Chandler | KO (Punches) |  | Bellator 243: Chandler vs Henderson 2 | Aug 07, 2020 | 1 | 2:09 | Uncasville, Connecticut, United States |
| Cancelled Bout | | Michael Chandler | - |  | Bellator 244: Chandler vs Henderson 2 | Jun 06, 2020 | - | - | Chicago, Illinois, United States |
| Win | 28-8 | Myles Jury | TKO (punches) |  | Bellator 227 | Sep 27, 2019 | 3 | 5:00 | Dublin, Ireland |
| Win | 27-8 | Adam Piccolotti | Decision (Split) |  | Bellator 220: MacDonald vs Fitch | Apr 27, 2019 | 3 | 5:00 | San Jose, California, United States |
| Win | 26-8 | Saad Awad | Decision (unanimous) |  | Bellator 208: Fedor vs Sonnen | Oct 13, 2018 | 3 | 5:00 | Long Island, New York, United States |
| Win | 25-8 | Roger Huerta | Submission (guillotine choke) |  | Bellator 196: Henderson vs Huerta | Apr 06, 2018 | 2 | 0:49 | Budapest, Hungary |
| Cancelled Bout | | Osman Kasimov  | - |  | FNG 86: Nam vs Zhumagulov | Apr 01, 2018 | - | - | Almaty, Kazakhstan |
| Loss | 24-8 | Patricky Freire  | Decision (split) |  | Bellator 183: Henderson vs Pitbull | Sep 23, 2017 | 3 | 5:00 | San Jose, California, United States |
| Loss | 24-7 | Michael Chandler | Decision (split) |  | Bellator 165: Chandler vs Henderson | Nov 19, 2016 | 5 | 5:00 | San Jose, California, United States |
| Win | 24-6 | Patricio Freire | TKO (leg injury) |  | Bellator 160: Henderson vs Pitbull | Aug 26, 2016 | 2 | 2:26 | Southaven, Mississippi, United States |
| Loss | 23-6 | Andrey Koreshkov | Decision (unanimous) |  | Bellator 153: Koreshkov vs Henderson | Apr 22, 2016 | 5 | 5:00 | Uncasville, United States |
| Win | 23-5 | Jorge Masvidal | Decision (Split) |  | UFC Fight Night: Henderson vs Masvidal | Nov 28, 2015 | 5 | 5:00 | Seoul, South Korea |
| Win | 22-5 | Brandon Thatch | Submission (rear-naked choke) | | UFC Fight Night: Henderson vs Thatch | Feb 14, 2015 | 4 | 3:58 | Broomfield, United States |
| Loss | 21-5 | Donald Cerrone | Decision (unanimous) |  | UFC Fight Night: McGregor vs Siver | Jan 18, 2015 | 3 | 5:00 | Boston, United States |
| Loss | 21-4 | Rafael dos Anjos | KO (punches) |  | UFC Fight Night: Henderson vs dos Anjos | Aug 23, 2014 | 1 | 2:31 | Tulsa, Oklahoma, United States |
| Win | 21-3 | Rustam Khabilov | Submission (rear-naked choke) |  | UFC Fight Night: Henderson vs Khabilov | Jun 07, 2014 | 4 | 1:16 | Albuquerque, United States |
| Win | 20-3 | Josh Thomson | Decision (split) |  | UFC on Fox 10: Henderson vs Thomson | Jan 25, 2014 | 5 | 5:00 | Chicago, United States |
| Loss | 19-3 | Anthony Pettis | Submission (armbar) | | UFC 164: Henderson vs Pettis 2 | Aug 31, 2013 | 1 | 4:31 | Milwaukee, United States |
| Win | 19-2 | Gilbert Melendez | Decision (split) | | UFC on FOX 7 | Apr 20, 2013 | 5 | 5:00 | HP Pavilion, San Jose, California |
| Win | 18-2 | Nate Diaz | Decision (unanimous) |  | UFC on Fox 5: Henderson vs Diaz | Dec 08, 2012 | 5 | 5:00 | Washington, United States |
| Win | 17-2 | Frankie Edgar | Decision (split) | | UFC 150 | Aug 11, 2012 | 5 | 5:00 | Denver, United States |
| Win | 16-2 | Frankie Edgar | Decision (unanimous) |  | UFC 144 | Feb 26, 2012 | 5 | 5:00 | Saitama, Saitama, Japan |
| Win | 15-2 | Clay Guida | Decision (unanimous) |  | UFC on Fox: Velasquez vs. dos Santos | Nov 12, 2011 | 3 | 5:00 | Anaheim, United States |
| Win | 14-2 | Jim Miller | Decision (unanimous) | | UFC Live: Hardy vs. Lytle | Aug 14, 2011 | 3 | 5:00 | Milwaukee, United States |
| Win | 13-2 | Mark Bocek | Decision (unanimous) |  | UFC 129 | Apr 30, 2011 | 3 | 5:00 | Toronto, Ontario, Canada |
| Loss | 12-2 | Anthony Pettis | Decision (unanimous) |  | WEC 53 | Dec 16, 2010 | 5 | 5:00 | Glendale, United States |
| Win | 12-1 | Donald Cerrone | Submission (guillotine choke) |  | WEC 48 | Apr 24, 2010 | 1 | 1:57 | Sacramento, United States |
| Win | 11-1 | Jamie Varner | Submission (guillotine choke) |  | WEC 46 | Jan 10, 2010 | 3 | 2:41 | Sacramento, United States |
| Win | 10-1 | Donald Cerrone | Decision (unanimous) |  | WEC 43 | Oct 10, 2009 | 5 | 5:00 | San Antonio, United States |
| Win | 9-1 | Shane Roller | TKO (punches) | | WEC 40 | Apr 05, 2009 | 1 | 1:41 | Chicago, Illinois, United States |
| Win | 8-1 | Anthony Njokuani | Submission (guillotine choke) | | WEC 38 | Jan 25, 2009 | 2 | 0:42 | San Diego, United States |
| Win | 7-1 | Diego Saraiva | Decision (unanimous) | | Evolution MMA | Oct 04, 2008 | 3 | 5:00 | Phoenix, Arizona, United States |
| Win | 6-1 | Ricardo Tirloni | Submission (guillotine choke) | | MFC 17 | Jul 25, 2008 | 2 | 3:49 | Edmonton, Alberta, Canada |
| Win | 5-1 | Mike Maestas | Submission (rear-naked choke) | | MFC 16: Anger Management | May 09, 2008 | 3 | 4:11 | Edmonton, Alberta, Canada |
| Win | 4-1 | Bryan Corley | Submission (rear-naked choke) | | VFC 21: Infamous | Dec 07, 2007 | 1 | 2:36 | Council Bluffs, United States |
| Win | 3-1 | David Dagloria | Submission (punches) | | UCE: Round 26: Episode 12 | Jun 23, 2007 | 1 | 1:45 | Ogden, Utah, United States |
| Loss | 2-1 | Rocky Johnson | Tech. Sub. (anaconda choke) | | Battlequest 5: Avalanche | Mar 31, 2007 | 1 | 0:46 | Vail, United States |
| Win | 2-0 | Allen Williams | TKO (punches) | | VFC 18: Hitmen | Feb 16, 2007 | 1 | 1:37 | Council Bluffs, United States |
| Win | 1-0 | Dan Gregary | Submission (punches) | | MCF: Genesis | Nov 18, 2006 | 1 | 4:21 | North Platte, United States |
