| Loss | 36-17-1 (1) | Jim Miller  | Submission (guillotine choke) |  | UFC 276: Adesanya vs Cannonier | Jul 02, 2022 | 2 | 1:32 | Las Vegas, Nevada, United States |
| Cancelled Bout | | Joe Lauzon | - |  | UFC Fight Night: Kattar vs Emmett | Jun 18, 2022 | - | - | Austin, Texas, United States |
| Cancelled Bout | | Joe Lauzon | - |  | UFC 274: Oliveira vs Gaethje | May 07, 2022 | - | - | Phoenix, Arizona, United States |
| Loss | 36-16-1 (1) | Alex Morono | TKO (punches) |  | UFC on ESPN 24: Rodriguez vs Waterson | May 08, 2021 | 1 | 4:40 | Las Vegas, Nevada, United States |
| Draw | 36-15-1 (1) | Niko Price | Draw (Majority) |  | UFC Fight Night 178: Covington vs Woodley | Sep 19, 2020 | 3 | 5:00 | Las Vegas, Nevada, United States |
| Loss | 36-15 (1) | Anthony Pettis | Decision (Unanimous) |  | UFC 249: Ferguson vs Gaethje | May 09, 2020 | 3 | 5:00 | Jacksonville, Florida, United States |
| Loss | 36-14 (1) | Conor McGregor  | TKO (Punches) |  | UFC 246: McGregor vs Cerrone | Jan 18, 2020 | 1 | 0:40 | Las Vegas, Nevada, United States |
| Loss | 36-13 (1) | Justin Gaethje | TKO (Punches) |  | UFC on ESPN+ 16: Cowboy vs Gaethje | Sep 14, 2019 | 1 | 4:18 | Vancouver, British Columbia, Canada |
| Loss | 36-12 (1) | Tony Ferguson | TKO (doctor stoppage) |  | UFC 238: Cejudo vs Moraes | Jun 08, 2019 | 2 | 5:00 | Chicago, Illinois, United States |
| Win | 36-11 (1) | Al Iaquinta | Decision (Unanimous) |  | UFC on ESPN+ 8: Iaquinta vs Cowboy | May 04, 2019 | 5 | 5:00 | Ottawa, Ontario, Canada |
| Win | 35-11 (1) | Alexander Hernandez | TKO (Head Kick and Punches) | | UFC on ESPN+ 1: Cejudo vs Dillashaw | Jan 19, 2019 | 2 | 3:42 | Brooklyn, New York, United States |
| Win | 34-11 (1) | Mike Perry | Submission (Armbar) | | UFC Fight Night 139: Korean Zombie vs Rodriguez | Nov 10, 2018 | 1 | 4:46 | Denver, Colorado, United States |
| Loss | 33-11 (1) | Leon Edwards  | Decision (Unanimous) |  | UFC Fight Night 132: Cowboy vs Edwards | Jun 23, 2018 | 5 | 5:00 | Singapore Indoor Stadium, Singapore  |
| Win | 33-10 (1) | Yancy Medeiros | TKO (Punches) | | UFC Fight Night 126: Cowboy vs Medeiros | Feb 18, 2018 | 1 | 4:58 | Austin, Texas, United States |
| Loss | 32-10 (1) | Darren Till  | TKO (Punches) |  | UFC Fight Night 118: Cowboy vs Till | Oct 21, 2017 | 1 | 4:20 | Gdansk, Poland |
| Loss | 32-9 (1) | Robbie Lawler | Decision (Unanimous) |  | UFC 214: Cormier vs Jones 2 | Jul 29, 2017 | 3 | 5:00 | Anaheim, California, United States |
| Loss | 32-8 (1) | Jorge Masvidal | TKO (punches) | | UFC on FOX 23: Shevchenko vs Peña | Jan 28, 2017 | 2 | 1:00 | Denver, Colorado, United States |
| Win | 32-7 (1) | Matt Brown | KO (Head Kick) |  | UFC 206: Holloway vs Pettis | Dec 10, 2016 | 3 | 0:34 | Toronto, Ontario, Canada |
| Win | 31-7 (1) | Rick Story | TKO (head kick and punches) | | UFC 202: Diaz vs McGregor 2 | Aug 20, 2016 | 2 | 2:02 | Las Vegas, Nevada, United States |
| Win | 30-7 (1) | Patrick Côté  | TKO (punches) |  | UFC Fight Night 89: MacDonald vs Thompson | Jun 18, 2016 | 3 | 2:35 | Ottawa, Ontario, Canada |
| Win | 29-7 (1) | Alex Oliveira  | Submission (triangle choke) |  | UFC Fight Night 83: Cowboy vs Olveira | Feb 21, 2016 | 1 | 2:33 | Pittsburgh, United States |
| Loss | 28-7 (1) | Rafael dos Anjos | TKO (Punches) | | UFC on Fox: Dos Anjos vs Cerrone 2 | Dec 19, 2015 | 1 | 1:06 | Orlando, United States |
| Win | 28-6 (1) | John Makdessi | TKO (retirement) | | UFC 187: Cormier vs Johnson | May 23, 2015 | 2 | 4:44 | Las Vegas, United States |
| Cancelled Bout | | Khabib Nurmagomedov  | - |  | UFC 187 | May 23, 2015 | - | - | Las Vegas, United States |
| Win | 27-6 (1) | Benson Henderson | Decision (unanimous) |  | UFC Fight Night: McGregor vs Siver | Jan 18, 2015 | 3 | 5:00 | Boston, United States |
| Win | 26-6 (1) | Myles Jury | Decision (unanimous) | | UFC 182: Jones vs Cormier | Jan 03, 2015 | 3 | 5:00 | Las Vegas, United States |
| Cancelled Bout | | Khabib Nurmagomedov | - |  | UFC 178 | Sep 27, 2014 | - | - | Las Vegas, United States |
| Win | 25-6 (1) | Eddie Alvarez | Decision (unanimous) |  | UFC 178: Johnson vs Cariaso | Sep 27, 2014 | 3 | 5:00 | Las Vegas, United States |
| Win | 24-6 (1) | Jim Miller | KO (head kick and punch) | | UFC Fight Night: Cerrone vs Miller | Jul 16, 2014 | 2 | 3:31 | Atlantic City, United States |
| Win | 23-6 (1) | Edson Barboza | Submission (rear-naked choke) |  | UFC on Fox 11: Werdum vs Browne | Apr 19, 2014 | 1 | 3:15 | Orlando, United States |
| Win | 22-6 (1) | Adriano Martins | KO (head kick) | | UFC on Fox 10 - Henderson vs Thomson | Jan 25, 2014 | 1 | 4:40 | Chicago, United States |
| Win | 21-6 (1) | Evan Dunham | Submission (triangle choke) | | UFC 167: St. Pierre vs Hendricks | Nov 16, 2013 | 2 | 3:49 | Las Vegas, United States |
| Loss | 20-6 (1) | Rafael dos Anjos | Decision (unanimous) | | UFC on Fox Sports 1 - Condit vs Kampmann | Aug 28, 2013 | 3 | 5:00 | Indianapolis, United States |
| Win | 20-5 (1) | K.J. Noons | Decision (unanimous) | | UFC 160: Velasquez vs Silva 2 | May 25, 2013 | 3 | 5:00 | Las Vegas, United States |
| Loss | 19-5 (1) | Anthony Pettis | TKO (kick to the body & punches) | | UFC on Fox: Johnson vs Dodson | Jan 26, 2013 | 1 | 2:35 | Chicago, United States |
| Win | 19-4 (1) | Melvin Guillard | KO (head kick & punch) | | UFC 150 | Aug 11, 2012 | 1 | 1:16 | Denver, United States |
| Win | 18-4 (1) | Jeremy Stephens | Decision (unanimous) | | UFC: Korean vs Poirier | May 15, 2012 | 3 | 5:00 | Fairfax, United States |
| Loss | 17-4 (1) | Nate Diaz | Decision (unanimous) | | UFC 141 | Dec 30, 2011 | 3 | 5:00 | Las Vegas, United States |
| Win | 17-3 (1) | Dennis Siver  | Submission (rear naked choke) |  | UFC 137: Penn vs Diaz | Oct 29, 2011 | 1 | 2:22 | Nevada, United States |
| Win | 16-3 (1) | Charles Oliveira | TKO (punches) | | UFC Live: Hardy vs Lytle | Aug 14, 2011 | 1 | 3:01 | Milwaukee, United States |
| Win | 15-3 (1) | Vagner Rocha | Decision (unanimous) | | UFC 131 | Jun 11, 2011 | 3 | 5:00 | Vancouver, Canada |
| Win | 14-3 (1) | Paul Kelly | Submission (rear-naked choke) | | UFC 126 | Feb 05, 2011 | 2 | 3:48 | Las Vegas, United States |
| Win | 13-3 (1) | Chris Horodecki | Submission (triangle choke) | | WEC 53 | Dec 16, 2010 | 2 | 2:43 | Glendale, United States |
| Win | 12-3 (1) | Jamie Varner | Decision (unanimous) | | WEC 51 | Sep 30, 2010 | 3 | 5:00 | Broomfield, United States |
| Loss | 11-3 (1) | Benson Henderson | Submission (guillotine choke) |  | WEC 48 | Apr 24, 2010 | 1 | 1:57 | Sacramento, United States |
| Win | 11-2 (1) | Ed Ratcliff | Submission (rear-naked choke) | | WEC 45 | Dec 19, 2009 | 3 | 3:47 | Las Vegas, United States |
| Loss | 10-2 (1) | Benson Henderson | Decision (unanimous) |  | WEC 43 | Oct 10, 2009 | 5 | 5:00 | San Antonio, United States |
| Win | 10-1 (1) | James Krause | Submission (rear-naked choke) | | WEC 41 | Jun 07, 2009 | 1 | 4:38 | Sacramento, United States |
| Loss | 9-1 (1) | Jamie Varner | Technical Decision (split) | | WEC 38 | Jan 25, 2009 | 5 | 3:10 | San Diego, United States |
| Win | 9-0 (1) | Rob McCullough | Decision (unanimous) | | WEC 36 | Nov 05, 2008 | 3 | 5:00 | Hollywood, United States |
| Win | 8-0 (1) | Danny Castillo | Submission (armbar) | | WEC 34 | Jun 01, 2008 | 1 | 1:30 | Sacramento, United States |
| NC | 7-0 (1) | Kenneth Alexander | No Contest: Overturned by NSAC | | WEC 30 | Sep 05, 2007 | 1 | 0:56 | Las Vegas, United States |
| Win | 7-0 | Yasunori Kanehara | Submission (triangle choke) | | GCM: Cage Force 3 | Jun 09, 2007 | 2 | 2:46 | Tokyo, Japan |
| Win | 6-0 | Anthony Njokuani | Submission (triangle choke) | | ROF 29: Aftershock | Apr 28, 2007 | 1 | 4:30 | Broomfield, United States |
| Win | 5-0 | Ryan Roberts | Submission (armbar) | | ROF 28: Evolution | Feb 16, 2007 | 1 | 1:49 | Broomfield, United States |
| Win | 4-0 | Jesse Brock | Submission (triangle choke) | | ROF 26: Relentless | Sep 09, 2006 | 1 | 1:35 | Colorado, United States |
| Win | 3-0 | Craig Tennant | Submission (armbar) | | ROF 24: Integrity | Jun 17, 2006 | 1 | 1:26 | Colorado, United States |
| Win | 2-0 | Cruz Chacon | Submission (triangle choke) | | ACF: Genesis | Feb 24, 2006 | 2 | 2:25 | Denver, United States |
| Win | 1-0 | Nate Mohr | Submission (The Meat Fondler) | | ROF 21: Full Blast | Feb 11, 2006 | 1 | 1:42 | Colorado, United States |
