| Niederlage | 16-8 | Eryk Anders  | TKO (Punches) |  | UFC 310: Pantoja vs Asakura | Dec 07, 2024 | 2 | 4:51 | Las Vegas, Nevada, United States |
| Cancelled Bout | | Eryk Anders | - |  | UFC 309: Jones vs Miocic | Nov 16, 2024 | - | - | New York City, New York, United States |
| Sieg | 16-7 | Bruno Silva  | Technical Decision (Unanimous) |  | UFC Fight Night: Blanchfield vs Fiorot | Mar 30, 2024 | 3 | 2:18 | Atlantic City, New Jersey, United States |
| Niederlage | 15-7 | Brad Tavares | Decision (Unanimous) |  | UFC 292: Sterling vs O'Malley | Aug 19, 2023 | 3 | 5:00 | Boston, Massachusetts, United States |
| Niederlage | 15-6 | Uriah Hall  | TKO (Leg Injury) |  | UFC 261: Usman vs Masvidal 2 | Apr 24, 2021 | 1 | 0:17 | Las Vegas, Nevada, United States |
| Sieg | 15-5 | Omari Akhmedov  | Decision (Unanimous) |  | UFC Fight Night: Lewis vs Oleinik | Aug 08, 2020 | 3 | 5:00 | Las Vegas, Nevada, United States |
| Cancelled Bout | | Jack Hermansson  | - |  | UFC on ESPN+ 32: Hermansson vs Weidman | May 02, 2020 | - | - | Oklahoma City, Oklahoma, United States |
| Niederlage | 14-5 | Dominick Reyes | KO (Punches) |  | UFC on ESPN2: Weidman vs Reyes | Oct 18, 2019 | 1 | 1:43 | Boston, Massachusetts, United States |
| Niederlage | 14-4 | Ronaldo Souza | KO (Punches) |  | UFC 230 | Nov 03, 2018 | 3 | 2:46 | New York City, New York, United States |
| Sieg | 14-3 | Kelvin Gastelum | Submission (arm-triangle choke) | | UFC on FOX 25: Weidman vs Gastelum | Jul 22, 2017 | 3 | 3:46 | Long Island, New York, United States |
| Niederlage | 13-3 | Gegard Mousasi  | TKO (knees) |  | UFC 210: Cormier vs Johnson 2 | Apr 08, 2017 | 2 | 3:13 | Buffalo, New York, United States |
| Niederlage | 13-2 | Yoel Romero  | KO (flying knee and punches) |  | UFC 205: Alvarez vs McGregor | Nov 12, 2016 | 3 | 0:24 | New York, New York, United States |
| Niederlage | 13-1 | Luke Rockhold | TKO (punches) | | UFC 194: Aldo vs McGregor | Dec 12, 2015 | 4 | 3:12 | Las Vegas, United States |
| Sieg | 13-0 | Vitor Belfort | TKO (punches) |  | UFC 187: Cormier vs Johnson | May 23, 2015 | 1 | 2:53 | Las Vegas, United States |
| Sieg | 12-0 | Lyoto Machida | Decision (unanimous) |  | UFC 175: Weidman vs Machida | Jul 05, 2014 | 5 | 5:00 | Las Vegas, United States |
| Sieg | 11-0 | Anderson Silva | TKO (leg injury) |  | UFC 168: Weidman vs Silva II | Dec 28, 2013 | 2 | 1:16 | Las Vegas, United States |
| Sieg | 10-0 | Anderson Silva | KO (punches) | | UFC 162: Silva vs Weidman | Jul 06, 2013 | 2 | 1:18 | Las Vegas, United States |
| Sieg | 9-0 | Mark Munoz | KO (elbow & punches) | | UFC on Fuel TV: Munoz vs. Weidman | Jul 11, 2012 | 2 | 1:37 | San Jose, United States |
| Sieg | 8-0 | Demian Maia | Decision (unanimous) |  | UFC on Fox: Evans vs. Davis | Jan 28, 2012 | 3 | 5:00 | Chicago, United States |
| Sieg | 7-0 | Tom Lawlor | Technical Submission | | UFC 139 | Nov 19, 2011 | 1 | 2:07 | San Jose, United States |
| Sieg | 6-0 | Jesse Bongfeldt | Submission (guillotine choke) | | UFC 131: Dos Santos vs. Carwin | Jun 11, 2011 | 1 | 4:54 | Vancouver, Canada |
| Sieg | 5-0 | Alessio Sakara  | Decision (unanimous) | | UFC Live: Sanchez vs. Kampmann | Mar 03, 2011 | 3 | 5:00 | Louisville, United States |
| Sieg | 4-0 | Valdir Araujo | Decision (unanimous) | | Ring of Combat 33 | Dec 03, 2010 | 3 | 5:00 | Atlantic City, United States |
| Sieg | 3-0 | Uriah Hall | TKO (punches) | | Ring of Combat 31 | Sep 24, 2010 | 1 | 3:06 | Atlantic City, United States |
| Sieg | 2-0 | Mike Stewart | TKO (punches) | | Ring of Combat 24 | Apr 17, 2009 | 1 | 2:38 | Atlantic City, United States |
| Sieg | 1-0 | Reubem Lopes | Submission (kimura) | | Ring of Combat 23 | Feb 20, 2009 | 1 | 1:35 | Atlantic City, United States |
